Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229357 | 0.77 | ALOX5 (0.55) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL3663172 | 0.77 | ALOX5 (0.55) | CA2ALOX5CA12CA1CA9 | |
| SCHEMBL5320663 | 0.76 | ALOX5 (0.49) | CA2ALOX5CA12CA1CA9 | |
| SCHEMBL336690 | 0.76 | ALOX5 (0.54) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL4985929 | 0.76 | ALOX5 (0.54) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL30733359 | 0.76 | ALOX5 (0.54) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL417540 | 0.73 | ALOX5 (0.64) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL243889 | 0.73 | ALOX5 (0.46) | CA2ALOX5CA12CA1CA9 | |
| SCHEMBL1706542 | 0.73 | ALOX5 (0.51) | CA2ALOX5AOC3DAOBRD4 | |
| SCHEMBL31299796 | 0.73 | ALOX5 (0.55) | ALOX5AOC3DAOBRD4DDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242767-A2 | N-dihydroindolyl ethyl-sulfon amides | BAYER AG (DE) | 1987-10-28 | — | — | EP | claimed |
| EP-0242767-A2 | N-dihydroindolyl ethyl-sulfon amides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |