Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003423 | 0.78 | ALOX5 (0.54) | ALOX5CA2KDM4EDAOMAPT | |
| SCHEMBL30508997 | 0.78 | ALOX5 (0.54) | ALOX5CA2KDM4EDAOMAPT | |
| SCHEMBL15416243 | 0.77 | KDM4E (0.55) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL10722048 | 0.76 | CA2 (0.53) | ALOX5CA2KDM4EDAOMAPT | |
| SCHEMBL9868223 | 0.76 | KDM4E (0.53) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL1767751 | 0.74 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL29875597 | 0.74 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| Alanine SCHEMBL28826582 | 0.74 | ALOX5 (0.57) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL25275820 | 0.73 | ALOX5 (0.59) | ALOX5KDM4EDAOMAPTHPGD | |
| SCHEMBL5851328 | 0.72 | ALOX5 (0.51) | ALOX5KDM4EDAOMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778633-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005123674-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |