SCHEMBL1072207

SCHEMBL1072207

O=c1ccc2nc3ccc(O)cc3oc-2c1.c1ccc(COCc2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.74
CYP1A2 P05177 1/20 0.53
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
PLEC Q15149 1/20 0.43
HTR2B P41595 1/20 0.40
AKR1B1 P15121 1/20 0.40
PDE4D Q08499 1/20 0.39
DAO P14920 1/20 0.38
SNCA P37840 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1093926 0.91 APP (0.60) APPCYP1A2MEN1POLBKMT2A
SCHEMBL6663297 0.88 APP (0.67) APPCYP1A2MEN1USP2POLB
SCHEMBL8066 0.86 APP (1.00) APPCYP1A2MEN1USP2POLB
Ammonia Solution, Strong SCHEMBL29419058 0.85 APP (0.97) APPCYP1A2MEN1USP2POLB
SCHEMBL1095367 0.85 APP (0.97) APPCYP1A2MEN1USP2POLB
SCHEMBL7113427 0.85 APP (0.97) APPCYP1A2MEN1USP2POLB
SCHEMBL29456578 0.85 APP (0.97) APPCYP1A2MEN1USP2POLB
Ether SCHEMBL1094032 0.84 APP (0.80) APPCYP1A2MEN1USP2POLB
Methoxymethane SCHEMBL2784008 0.84 APP (0.89) APPCYP1A2MEN1USP2POLB
Benzoic Acid SCHEMBL21043906 0.83 APP (0.78) APPCYP1A2MEN1USP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606625-B2 Antibody binding specifically to B7—H3 and use thereof Y-Biologics Inc. (KR) 2026-04-21 US disclosed
US-20260072014-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEUROLOGICAL DISEASES COMPRISING HIGHLY POTENT STEM CELLS EXPRESSING TIMP-1, MCP-1, GROa, AND IL-6, AND METHOD FOR SELECTING HIGHLY POTENT STEM CELLS MEDINNO INC (KR) 2026-03-12 US disclosed
US-20260028418-A1 ANTI-HER2 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF, AND CHIMERIC ANTIGEN RECEPTOR COMPRISING SAME GC CELL CORP (KR) 2026-01-29 US disclosed
US-12473366-B2 Anti-TIE2 antibody and use thereof PHARMABCINE INC. (KR) 2025-11-18 US disclosed
EP-4640850-A2 METHOD FOR ASSESSING PROGNOSIS OR RISK STRATIFICATION OF LIVER CANCER BY USING CPG METHYLATION VARIATION IN GENE Lepidyne Co., Ltd. (KR) 2025-10-29 EP disclosed
EP-4640710-A1 MONOCLONAL ANTIBODY SPECIFICALLY BINDING TO CLAUDIN-18.2 AND USE THEREOF Y-Biologics Inc. (KR) 2025-10-29 EP disclosed
US-12448436-B2 Antibody specifically binding to GRP94 or antigen-binding fragment thereof, and uses thereof KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2025-10-21 US disclosed
US-12410261-B2 Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same GC Cell Corporation (KR) 2025-09-09 US disclosed
US-12371736-B2 TD probe and its uses SEEGENE, INC. (KR) 2025-07-29 US disclosed
CN-119895261-A Pharmaceutical composition for preventing or treating nervous system diseases comprising high-efficiency stem cells expressing TIMP-1, MCP-1, GROα and IL-6, and method for selecting high-efficiency stem cells 美迪因诺医疗创新科技有限公司 2025-04-25 CN disclosed
EP-1210342-A1 THE USE OF FLUORESCEIN ARYL ETHERS IN HIGH THROUGHPUT CYTOCHROME P450 INHIBITION ASSAYS GENTEST CORPORATION (US) 2002-06-05 EP disclosed
US-20020045620-A1 Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC 2002-04-18 US disclosed
US-20010056183-A1 Sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION 2001-12-27 US disclosed
EP-1147216-A1 RESORUFIN DERIVATIVES AS SUBSTRATES FOR CYP3A4 SMITHKLINE BEECHAM PLC (GB) 2001-10-24 EP disclosed
EP-1140888-A1 OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY Aurora Biosciences Corporation (US) 2001-10-10 EP disclosed
WO-2001049685-A2 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 2001-07-12 WO disclosed
WO-2001014361-A1 THE USE OF FLUORESCEIN ARYL ETHERS IN HIGH THROUGHPUT CYTOCHROME P450 INHIBITION ASSAYS GENTEST CORPORATION (US) 2001-03-01 WO disclosed
US-6143492-A COMPOUND USEFUL AS AN OPTICAL PROBE; DRUG SCREENING AURORA BIOSCIENCES CORPORATION (US) 2000-11-07 US disclosed
WO-2000044933-A1 RESORUFIN DERIVATIVES AS SUBSTRATES FOR CYP3A4 SMITHKLINE BEECHAM P.L.C. (GB) 2000-08-03 WO disclosed
WO-2000035900-A1 OPTICAL MOLECULAR SENSORS FOR CYTOCHROME P450 ACTIVITY AURORA BIOSCIENCES CORPORATION (US) 2000-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606625-B2 Antibody binding specifically to B7—H3 and use thereof IGSF11, CD274, TNFRSF9 APP 2915/4885CYP1A2 3663/4885MEN1 1512/4885
US-20260028418-A1 ANTI-HER2 ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF, AND CHIMERIC ANTIGEN RECEPTOR COMPRISING SAME IGSF11, BCR, PDCD1LG2 APP 3039/4885CYP1A2 4592/4885MEN1 4357/4885
US-20020045620-A1 Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis in mammals LIPA, PNLIP, PCSK9 APP 2077/4885CYP1A2 39/4885MEN1 4579/4885
US-20260072014-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEUROLOGICAL DISEASES COMPRISING HIGHLY POTENT STEM CELLS EXPRESSING TIMP-1, MCP-1, GROa, AND IL-6, AND METHOD FOR SELECTING HIGHLY POTENT STEM CELLS IL6, IL1A, CCR6 APP 73/4885CYP1A2 2423/4885MEN1 3008/4885
US-20010056183-A1 Sulfonamides and derivatives thereof that modulate the activity of endothelin EDNRA, EDNRB, ECE1 APP 2352/4885CYP1A2 3756/4885MEN1 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.