SCHEMBL10723741

SCHEMBL10723741

Nc1cccc2c1C(=O)c1cccc(NC(=O)c3cccc(Cl)c3)c1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
MMP14 P50281 1/20 0.54
KCNMA1 Q12791 1/20 0.51
CASP3 P42574 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.48
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 1/20 0.47
RXFP1 Q9HBX9 1/20 0.46
KCNK3 O14649 2/20 0.46
KCNK9 Q9NPC2 2/20 0.46
MAPT P10636 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SNCA P37840 1/20 0.46
KCNQ3 O43525 1/20 0.45
KCNQ2 O43526 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10723796 0.96 MEN1 (0.50) MEN1KMT2AMMP14KCNMA1CASP3
SCHEMBL11413623 0.92 KCNMA1 (0.58) MEN1KMT2AKCNMA1CASP3L3MBTL1
SCHEMBL10726032 0.87 MEN1 (0.56) MEN1KMT2AMMP14CASP3L3MBTL1
SCHEMBL10726036 0.86 MEN1 (0.74) MEN1KMT2AMMP14KCNMA1RXFP1
SCHEMBL1982461 0.85 MEN1 (0.72) MEN1KMT2AMMP14CASP3HDAC3
SCHEMBL30611003 0.85 MEN1 (0.72) MEN1KMT2AMMP14CASP3HDAC3
SCHEMBL10723748 0.84 KDM4E (0.53) MEN1KMT2AMMP14CASP3RXFP1
SCHEMBL10728256 0.84 MEN1 (0.52) MEN1KMT2AMMP14CASP3L3MBTL1
SCHEMBL6424210 0.83 MEN1 (0.60) MEN1KMT2AMMP14KCNMA1CASP3
SCHEMBL8777783 0.82 MEN1 (0.67) MEN1KMT2AMMP14CASP3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4709019-A COLORFAST PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
EP-0043937-B1 ANTHRAQUINONE-AZO COMPOUNDS, THEIR PREPARATION AND THEIR USE BAYER AG (DE) 1984-09-19 EP disclosed
EP-0058866-B1 ANTHRAQUINONE-AZO COMPOUNDS, THEIR PREPARATION AND USE BAYER AG (DE) 1984-07-18 EP disclosed
US-4389215-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1983-06-21 US disclosed
EP-0023666-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AS WELL AS A PROCESS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-10-13 EP disclosed
EP-0058866-A1 Anthraquinone-azo compounds, their preparation and use BAYER AG (DE) 1982-09-01 EP disclosed
EP-0023648-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION; PROCESS FOR DYEING SYNTHETIC FIBRE MATERIALS AS WELL AS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-06-23 EP disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4319025-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
EP-0043937-A2 Anthraquinone-azo compounds, their preparation and their use BAYER AG (DE) 1982-01-20 EP disclosed
EP-0023617-A1 Anthraquinone-azo compounds, process for their preparation and their use as pigments BAYER AG (DE) 1981-02-11 EP disclosed
EP-0023666-A1 Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed
EP-0023648-A1 Anthraquinone-azomethine compounds, process for their preparation; process for dyeing synthetic fibre materials as well as for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed