Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726036 | 0.92 | MEN1 (0.74) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL11413623 | 0.90 | KCNMA1 (0.58) | MEN1KMT2AKCNMA1KCNK3KCNK9 | |
| SCHEMBL13656878 | 0.87 | MEN1 (0.51) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL11299034 | 0.86 | MEN1 (0.56) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL11299151 | 0.84 | MEN1 (0.54) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL6417715 | 0.84 | KMT2A (0.69) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL6419867 | 0.83 | MEN1 (0.82) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL30544874 | 0.83 | MEN1 (0.82) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL6421461 | 0.83 | MEN1 (0.60) | MEN1KMT2AMMP14CYP1A2TSHR | |
| SCHEMBL10723741 | 0.83 | MEN1 (0.54) | MEN1KMT2AMMP14CYP1A2KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | HUANG HSU-SHAN (TW) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009924-A1 | Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives | NFE2L2, NR2F2, TFAM | MEN1 4402/4885KMT2A 1696/4885MMP14 2848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.