Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27692286 | 0.84 | POLB (0.42) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1751418 | 0.82 | POLB (0.43) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11019559 | 0.80 | LMNA (0.51) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1751839 | 0.75 | POLB (0.39) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16165963 | 0.74 | — | — | |
| SCHEMBL20101662 | 0.74 | POLB (0.41) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10723840 | 0.73 | NPSR1 (0.37) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11581057 | 0.73 | ALOX15 (0.48) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9662247 | 0.72 | ALDH1A1 (0.40) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6736700 | 0.71 | POLB (0.46) | POLBALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245066-A2 | Method for plant growth regulation | ELI LILLY AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4704156-A | TRIHALOCYCLOPROPANECARBOXYLIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-11-03 | — | — | US | disclosed |