Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL10720284 | 1.00 | KCNH2 (0.64) | KCNH2DRD3CHRM3KDM4ELMNA | |
| Benzamide SCHEMBL10721865 | 0.86 | DRD2 (0.61) | KCNH2DRD3KDM4ESIGMAR1BLM | |
| Decane SCHEMBL28230778 | 0.85 | MAPT (0.67) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL10723980 | 0.84 | SIGMAR1 (0.70) | KCNH2DRD3CHRM3SIGMAR1BLM | |
| SCHEMBL10724043 | 0.84 | SIGMAR1 (0.70) | KCNH2DRD3CHRM3SIGMAR1BLM | |
| SCHEMBL10722011 | 0.84 | SIGMAR1 (0.70) | KCNH2DRD3CHRM3SIGMAR1BLM | |
| Benzamide SCHEMBL28124928 | 0.83 | CYP3A4 (0.70) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL16980657 | 0.82 | SIGMAR1 (0.72) | KCNH2DRD3KDM4ESIGMAR1BLM | |
| Benzamide SCHEMBL22117133 | 0.80 | CYP3A4 (0.70) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL1286766 | 0.80 | KCNH2 (0.52) | KCNH2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4613878-A | DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS | RICOH COMPANY, LTD. (JP) | 1986-09-23 | — | — | US | disclosed |