Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730848 | 0.86 | ALPG (0.40) | ALPLALPGPLAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10727036 | 0.84 | AGTR1 (0.40) | L3MBTL1ALPGPLAA | |
| SCHEMBL10724414 | 0.77 | POLB (0.40) | LMNAL3MBTL1ALPLALPGALPI | |
| SCHEMBL10650764 | 0.75 | HTT (0.47) | LMNAKMT2AGLSSMN1; SMN2ALDH1A1 | |
| SCHEMBL10724330 | 0.75 | TBXAS1 (0.54) | — | |
| SCHEMBL10646375 | 0.71 | MEN1 (0.44) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10724345 | 0.70 | TBXAS1 (0.45) | SMN1; SMN2FDPS | |
| SCHEMBL10727088 | 0.70 | POLB (0.44) | LMNAALPLALPGALPIPLAA | |
| SCHEMBL10724377 | 0.69 | STING1 (0.36) | L3MBTL1KMT2A | |
| SCHEMBL6917802 | 0.69 | DAO (0.60) | LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643998-A | Imidazolylalkylthienyl tetrahydropyridazines and processes for their use | A. NATTERMAN & CIE GMBH (DE) | 1987-02-17 | — | — | US | disclosed |