Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727036 | 0.91 | AGTR1 (0.40) | ALPGPLAAAGTR1AGTR2HDAC1 | |
| SCHEMBL10724349 | 0.86 | LMNA (0.39) | ALPGPLAAALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL10729449 | 0.78 | POLB (0.41) | ALPGPLAAALPLCA12CA1 | |
| SCHEMBL10650764 | 0.76 | HTT (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10724330 | 0.73 | TBXAS1 (0.54) | — | |
| SCHEMBL27886864 | 0.71 | SMN1; SMN2 (0.58) | ALPGPLAAALPLCA12CA1 | |
| SCHEMBL10646375 | 0.70 | MEN1 (0.44) | ALDH1A1SMN1; SMN2HDAC1 | |
| SCHEMBL10730533 | 0.69 | POLB (0.43) | ALPGPLAAALPLALDH1A1AGTR1 | |
| SCHEMBL10724252 | 0.68 | PDE4A (0.37) | ALPGPLAAALPLCA12CA1 | |
| SCHEMBL10724377 | 0.68 | STING1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643998-A | Imidazolylalkylthienyl tetrahydropyridazines and processes for their use | A. NATTERMAN & CIE GMBH (DE) | 1987-02-17 | — | — | US | disclosed |