Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159006 | 0.86 | KDM4E (0.60) | KDM4ENPSR1ALDH1A1MCL1HPGD | |
| SCHEMBL8572725 | 0.85 | LCK (0.56) | KDM4ENPSR1ALDH1A1MCL1HPGD | |
| SCHEMBL10958648 | 0.83 | KDM4E (0.52) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| SCHEMBL10721933 | 0.83 | PKM (0.56) | KDM4ENPSR1ALDH1A1MCL1HPGD | |
| SCHEMBL7377807 | 0.83 | KDM4E (0.52) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| SCHEMBL3313702 | 0.81 | ADRA2A (0.53) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| SCHEMBL29510768 | 0.81 | ADRA2A (0.53) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| SCHEMBL10561340 | 0.79 | KDM4E (0.56) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| Water SCHEMBL7373734 | 0.79 | ADRA2A (0.52) | KDM4ENPSR1ALDH1A1HPGDTSHR | |
| SCHEMBL7377119 | 0.77 | KDM4E (0.47) | KDM4ENPSR1ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |