SCHEMBL29510768

SCHEMBL29510768

CCS(=O)(=O)c1cc(C(=O)O)c(OC)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRA2A P08913 2/20 0.53
▸ DRD3 P35462 2/20 0.53
▸ TSHR P16473 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ DRD2 P14416 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ ADRA2B P18089 1/20 0.53
▸ ADRA2C P18825 1/20 0.53
▸ HTR2A P28223 1/20 0.53
▸ MAPK1 P28482 1/20 0.53
▸ HTR7 P34969 1/20 0.53
▸ HRH1 P35367 1/20 0.53
▸ HTR2B P41595 1/20 0.53
▸ KCNH2 Q12809 1/20 0.53
▸ HRH3 Q9Y5N1 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ ALDH1A1 P00352 3/20 0.47
▸ HPGD P15428 2/20 0.44
▸ LCK P06239 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3313702 1.00 ADRA2A (0.53) ADRA2ADRD3TSHRLMNADRD2
Water SCHEMBL7373734 0.98 ADRA2A (0.52) ADRA2ADRD3TSHRLMNADRD2
Ethylene Glycol SCHEMBL29225457 0.96 ADRA2A (0.50) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL7377119 0.90 KDM4E (0.47) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL13395713 0.90 TSHR (0.47) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL24694102 0.88 DRD2 (0.53) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL28430952 0.88 LMNA (0.52) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL12070949 0.87 GAA (0.57) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL31376269 0.87 GAA (0.57) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL28339029 0.87 DRD2 (0.52) ADRA2ADRD3TSHRLMNADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022256482-A1 METHODS FOR PREPARING CRYSTALLINE FORMS OF AMISULPRIDE SUNOVION PHARMACEUTICALS INC. (US) 2022-12-08 — — WO claimed
CN-118993969-B Industrial production method for amisulpride 广州市桐晖药业有限公司 2025-01-24 — — CN disclosed
CN-118993969-A Industrial production method for amisulpride 广州市桐晖药业有限公司 2024-11-22 — — CN disclosed
CN-118593482-A Non-racemic mixture and use thereof 赛诺维信制药公司 2024-09-06 — — CN disclosed
CN-117865861-A Amisulpride impurity J and preparation method thereof 常州康普药业有限公司 2024-04-12 — — CN disclosed
CN-116239505-A Method for preparing amisulpride intermediate amiloride 浙江华海药业股份有限公司 2023-06-09 — — CN disclosed
WO-2022256482-A1 METHODS FOR PREPARING CRYSTALLINE FORMS OF AMISULPRIDE SUNOVION PHARMACEUTICALS INC. (US) 2022-12-08 — — WO disclosed
CN-112624951-B Preparation method of amisulpride 江苏阿尔法药业股份有限公司 2022-05-10 — — CN disclosed
EP-3980009-A1 MODIFIED RELEASE FORMULATIONS AND USES THEREOF Sunovion Pharmaceuticals Inc. (US) 2022-04-13 — — EP disclosed
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