Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728507 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10727279 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10727275 | 0.87 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10719220 | 0.87 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10732557 | 0.85 | MAPT (0.40) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10732553 | 0.85 | MAPT (0.40) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10731572 | 0.84 | PGR (0.41) | ALDH1A1LMNASMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL10731566 | 0.84 | PGR (0.41) | ALDH1A1LMNASMN1; SMN2HSD11B1MEN1 | |
| SCHEMBL10730534 | 0.83 | HTR6 (0.50) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT | |
| SCHEMBL10730524 | 0.83 | HTR6 (0.50) | ALDH1A1LMNASMN1; SMN2HSD11B1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |