Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732553 | 1.00 | MAPT (0.40) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10719220 | 0.88 | ALDH1A1 (0.45) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10728511 | 0.85 | ALDH1A1 (0.39) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10728507 | 0.85 | ALDH1A1 (0.39) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10732024 | 0.84 | MAPT (0.52) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10732032 | 0.84 | MAPT (0.52) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10730534 | 0.84 | HTR6 (0.50) | MAPTHSD11B1ALDH1A1LMNATP53 | |
| SCHEMBL10730524 | 0.84 | HTR6 (0.50) | MAPTHSD11B1ALDH1A1LMNATP53 | |
| SCHEMBL10727275 | 0.83 | ALDH1A1 (0.46) | MAPTHSD11B1ALDH1A1LMNAGAA | |
| SCHEMBL10727279 | 0.83 | ALDH1A1 (0.46) | MAPTHSD11B1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |