Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | FHIT | P49789 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10459386 | 0.86 | L3MBTL1 (0.47) | L3MBTL1POLBSMN1; SMN2GLAFHIT | |
| SCHEMBL7288512 | 0.85 | L3MBTL1 (0.50) | L3MBTL1POLBSMN1; SMN2GLAFHIT | |
| SCHEMBL14060872 | 0.82 | L3MBTL1 (0.47) | L3MBTL1POLBSMN1; SMN2GLAFHIT | |
| SCHEMBL10733976 | 0.80 | L3MBTL1 (0.49) | L3MBTL1POLBSMN1; SMN2GLAFHIT | |
| SCHEMBL5379717 | 0.77 | L3MBTL1 (0.63) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL2059383 | 0.76 | POLB (0.58) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL5699380 | 0.75 | PKM (0.54) | L3MBTL1POLBSMN1; SMN2GLAFHIT | |
| SCHEMBL11603936 | 0.74 | TDP1 (0.56) | L3MBTL1POLBSMN1; SMN2GLAPTGDR2 | |
| SCHEMBL3064143 | 0.73 | TSHR (0.70) | POLBSMN1; SMN2PTGDR2TDP1TSHR | |
| SCHEMBL2113005 | 0.73 | PTGDR2 (0.64) | POLBSMN1; SMN2PTGDR2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072211-B1 | RADIATION STERILIZABLE ABSORBABLE POLYMERIC MATERIALS AND METHODS FOR MANUFACTURING THE SAME | ETHICON, INC. (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4689424-A | POLYESTERS | ETHICON, INC. (US) | 1987-08-25 | — | — | US | disclosed |
| US-4649921-A | ABSORBABLE SUTURES FOR SURGERY | ETHICON, INC. (US) | 1987-03-17 | — | — | US | disclosed |
| US-4546152-A | Poly(p-dioxanone) polymers having improved radiation resistance | ETHICON, INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4435590-A | Radiation sterilizable absorbable polymeric materials and methods for manufacturing the same | ETHICON, INC. (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0072211-A2 | Radiation sterilizable absorbable polymeric materials and methods for manufacturing the same | ETHICON, INC. (US) | 1983-02-16 | — | — | EP | disclosed |