SCHEMBL5379717

SCHEMBL5379717

Cc1c(OCC(=O)O)cccc1OCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.63
POLB P06746 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
GLA P06280 1/20 0.63
KDM4E B2RXH2 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
ALDH1A1 P00352 2/20 0.59
HPGD P15428 2/20 0.59
PTGDR2 Q9Y5Y4 4/20 0.55
ALOX15 P16050 1/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
CASP1 P29466 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KMT2A Q03164 1/20 0.50
LMNA P02545 1/20 0.50
CD69 Q07108 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059383 0.90 POLB (0.58) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL6746949 0.89 L3MBTL1 (0.56) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL1887192 0.87 KMT2A (0.61) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL29040313 0.87 L3MBTL1 (0.54) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL7654284 0.86 L3MBTL1 (0.55) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL19086322 0.84 PTGDR2 (0.61) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL340762 0.82 L3MBTL1 (0.80) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL29682135 0.82 L3MBTL1 (0.80) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL17847080 0.82 ALDH1A1 (0.55) L3MBTL1POLBSMN1; SMN2GLAKDM4E
SCHEMBL8156825 0.82 L3MBTL1 (0.49) L3MBTL1POLBSMN1; SMN2GLAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6254950-B1 BLEND WITH POLYETHYLENE TEREPHTHALATE AND NAPHTHALATE, POLYBUTYLENE AND POLYTRIMETHYLENE TEREPHTHALATE, AND/OR POLYBUTYLENE NAPHTHALATE; PACKAGING EASTMAN CHEMICAL COMPANY 2001-07-03 US claimed
US-5030705-A Packaging material MITSUBISHI KASEI CORPORATION (JP) 1991-07-09 US claimed
EP-0335594-A2 Copolymerized polymer Mitsubishi Chemical Corporation (JP) 1989-10-04 EP claimed
US-7276571-B2 Process for making phenylene dioxydiacetic acid and use thereof INDSPEC CHEMICAL CORPORATION 2007-10-02 US disclosed
WO-2007005086-A1 PROCESS FOR MAKING PHENYLENE DIOXYDIACETIC ACID AND USE THEREOF INDSPEC CHEMICAL CORPORATION (US) 2007-01-11 WO disclosed
US-20070004898-A1 Process for making phenylene dioxydiacetic acid and use thereof INDSPEC CHEMICAL CORPORATION 2007-01-04 US disclosed
EP-0492999-B1 Copolyester and hollow container and oriented film comprising the copolyester MITSUBISHI CHEM CORP (JP) 2002-05-22 EP disclosed
US-6254950-B1 BLEND WITH POLYETHYLENE TEREPHTHALATE AND NAPHTHALATE, POLYBUTYLENE AND POLYTRIMETHYLENE TEREPHTHALATE, AND/OR POLYBUTYLENE NAPHTHALATE; PACKAGING EASTMAN CHEMICAL COMPANY 2001-07-03 US disclosed
US-20010003775-A1 Method for producing a copolymerized polyester resin MITSUBISHI CHEMICAL CORPORATION (JP) 2001-06-14 US disclosed
US-6239249-B1 COPOLYMERIZATION OF TEREPHTHALIC ACID OR ITS DIESTER AND A SOLUTION OF A PHENOXYDIOXYDIACETIC ACID IN ETHYLENE GLYCOL MITSUBISHI CHEMICAL CORPORATION (JP) 2001-05-29 US disclosed
US-5239045-A Containing terephthalic acid, phenylenedioxy/diacetic acid, diol; packaging MITSUBISHI KASEI CORPORATION (JP) 1993-08-24 US disclosed
EP-0492999-A2 Copolyester and hollow container and oriented film comprising the copolyester Mitsubishi Chemical Corporation (JP) 1992-07-01 EP disclosed
US-5030705-A Packaging material MITSUBISHI KASEI CORPORATION (JP) 1991-07-09 US disclosed
US-4959421-A PHENYLENEBIS/OXYACETIC ACID/ MITSUBISHI KASEI CORPORATION (JP) 1990-09-25 US disclosed
EP-0335594-A2 Copolymerized polymer Mitsubishi Chemical Corporation (JP) 1989-10-04 EP disclosed