Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 5/20 | 0.47 |
| ▸ | MMP13 | P45452 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727300 | 0.94 | KMT2A (0.47) | PKMMMP13MMP8MMP2GAA | |
| SCHEMBL10727301 | 0.94 | KMT2A (0.47) | PKMMMP13MMP8MMP2GAA | |
| SCHEMBL10731670 | 0.83 | MAPT (0.43) | MMP13MMP1MMP8MMP9CA1 | |
| SCHEMBL10716590 | 0.82 | MEN1 (0.44) | MMP13MMP1MMP8MMP9CA1 | |
| SCHEMBL10732518 | 0.82 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL10732521 | 0.82 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL10719220 | 0.81 | ALDH1A1 (0.45) | GAAHTTHPGDALDH1A1NPC1 | |
| SCHEMBL5860986 | 0.80 | ALDH1A1 (0.43) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL5860990 | 0.80 | ALDH1A1 (0.43) | PKMMMP13MMP1CA1CA2 | |
| SCHEMBL10732024 | 0.78 | MAPT (0.52) | GAAHTTHPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4647569-A | Antiarthritic pyridylaminoethene disulfonyl compounds and use | MAY & BAKER LIMITED (GB) | 1987-03-03 | — | — | US | disclosed |