Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254716 | 0.92 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL4740313 | 0.92 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL12215808 | 0.88 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL526722 | 0.85 | MEN1 (0.39) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL25209687 | 0.84 | MEN1 (0.53) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL28481211 | 0.84 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL4740322 | 0.82 | MEN1 (0.37) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL15624149 | 0.82 | MEN1 (0.40) | MEN1KMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL21192369 | 0.81 | MEN1 (0.33) | MEN1KMT2APKMKDM4EMAPT | |
| SCHEMBL9785125 | 0.81 | MMP8 (0.44) | MEN1KMT2AALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210237045-A1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | APEIRON SYNTHESIS S.A. (PL) | 2021-08-05 | — | — | US | disclosed |
| US-10828628-B2 | Homogeneous catalysts that are recoverable by host-guest interactions | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190344255-A1 | Homogeneous Catalysts That Are Recoverable By Host Guest Interactions | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-11-14 | — | — | US | disclosed |
| EP-3068768-B1 | ANTIDIABETIC TRICYCLIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2019-07-31 | — | — | EP | disclosed |
| EP-3068768-B1 | ANTIDIABETIC TRICYCLIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10357763-B2 | Homogeneous catalysts that are recoverable by host guest interactions | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| WO-2011059803-A2 | RUTHENIUM-ALKYLIDENES CONTAINING ACYCLIC DIAMINOCARBENES FOR OBTAINING LOW E/Z RATIOS IN CROSS METATHESIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-2276745-A1 | RUTHENIUM OLEFIN METATHESIS CATALYSTS BEARING N-HETEROCYCLIC CARBENE LIGANDS WITH SUBSTITUTED BACKBONE | Materia, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009126831-A1 | RUTHENIUM OLEFIN METATHESIS CATALYSTS BEARING N-HETEROCYCLIC CARBENE LIGANDS WITH SUBSTITUTED BACKBONE | MATERIA, INC. (US) | 2009-10-15 | — | — | WO | disclosed |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-12-06 | — | — | US | disclosed |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-12-06 | — | — | US | disclosed |
| WO-2007075427-A1 | ORGANOMETALLIC RUTHENIUM COMPLEXES AND RELATED METHODS FOR THE PREPARATION OF TETRA-SUBSTITUTED AND OTHER HINDERED OLEFINS | MATERIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-1743899-A1 | Metal complexes for use in metathesis, atom transfer radical reactions, addition polymerisation and vinylation reactions, methods and intermediates for making them | Universiteit Gent (BE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1468004-B1 | METAL COMPLEXES FOR USE IN METATHESIS | UNIV GENT (BE) | 2006-12-20 | — | — | EP | disclosed |
| US-6921736-B1 | Simply assembled and recyclable polymer-supported olefin metathesis catalysts | UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION, INC. (US) | 2005-07-26 | — | — | US | disclosed |
| EP-1329455-A1 | Metal carbene complexes, methods and intermediates for making them and their use in metathesis reactions | UNIVERSITEIT GENT (BE) | 2003-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190344255-A1 | Homogeneous Catalysts That Are Recoverable By Host Guest Interactions | BLM, INTS9, INF2 | MEN1 482/4885KMT2A 2993/4885ALDH1A1 2397/4885 |
| US-20210237045-A1 | USE OF N-CHELATING RUTHENIUM COMPLEXES IN THE METATHESIS REACTION | CYC1, AP1M1, HNMT | MEN1 1082/4885KMT2A 4223/4885ALDH1A1 1856/4885 |
| US-20070282148-A1 | Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins | ORC3, OXER1, CBR3 | MEN1 1476/4885KMT2A 2953/4885ALDH1A1 2951/4885 |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | MEN1 1935/4885KMT2A 3381/4885ALDH1A1 1395/4885 |
| US-10357763-B2 | Homogeneous catalysts that are recoverable by host guest interactions | BLM, INTS9, INF2 | MEN1 482/4885KMT2A 2993/4885ALDH1A1 2397/4885 |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | MEN1 796/4885KMT2A 3683/4885ALDH1A1 4132/4885 |
| US-10828628-B2 | Homogeneous catalysts that are recoverable by host-guest interactions | BLM, INTS9, SOD1 | MEN1 445/4885KMT2A 2985/4885ALDH1A1 2229/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | MEN1 1935/4885KMT2A 3381/4885ALDH1A1 1395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.