Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22604931 | 0.89 | NOS3 (0.36) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL11142100 | 0.80 | SHBG (0.39) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL9875129 | 0.79 | ESR1 (0.47) | ALDH1A1TP53CYP3A4TSHRTDP1 | |
| SCHEMBL11694229 | 0.78 | GABRA1 (0.38) | TSHRNOS3NOS1NOS2POLB | |
| SCHEMBL28463478 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CYP3A4TSHRTDP1NOS3 | |
| SCHEMBL28117219 | 0.76 | GABRA1 (0.50) | ALDH1A1NOS3NOS1NOS2POLB | |
| SCHEMBL22604922 | 0.76 | NOS3 (0.39) | ALDH1A1CYP3A4TSHRNOS3NOS1 | |
| SCHEMBL8186747 | 0.76 | CA1 (0.46) | GABRA1GABRB2PTGS1PTGS2ESR1 | |
| SCHEMBL1312347 | 0.76 | GABRA1 (0.46) | ALDH1A1TSHRPOLBGABRA1GABRB2 | |
| SCHEMBL11511762 | 0.76 | SKP2 (0.53) | ALDH1A1CYP3A4TSHRTDP1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11913944-B2 | Photoaffinity probes | PROMEGA CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-20200340982-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION | 2020-10-29 | — | — | US | disclosed |
| US-8481546-B2 | CGRP receptor antagonist | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120059017-A1 | CGRP Receptor Antagonist | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059017-A1 | CGRP Receptor Antagonist | CALCRL, PTGIR, CALCR | ALDH1A1 1718/4885TP53 1972/4885CYP3A4 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.