Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744270 | 0.89 | NPSR1 (0.53) | SMN1; SMN2NPSR1CYP3A4RXFP1TSHR | |
| SCHEMBL10735118 | 0.83 | ALDH1A1 (0.51) | SMN1; SMN2NPSR1HSD17B10L3MBTL1 | |
| SCHEMBL10741723 | 0.76 | CYP3A4 (0.50) | SMN1; SMN2NPSR1CYP3A4RXFP1TSHR | |
| SCHEMBL10737935 | 0.75 | KMT2A (0.46) | SMN1; SMN2NPSR1TSHR | |
| SCHEMBL10739941 | 0.74 | PLA2G1B (0.47) | SMN1; SMN2NPSR1CYP3A4RXFP1PLA2G1B | |
| SCHEMBL10739859 | 0.73 | RORA (0.46) | SMN1; SMN2NPSR1RXFP1HSD17B10 | |
| SCHEMBL10741313 | 0.73 | NPSR1 (0.55) | SMN1; SMN2NPSR1CYP3A4RXFP1HSD17B10 | |
| SCHEMBL10735119 | 0.71 | TDP1 (0.57) | SMN1; SMN2NPSR1CYP3A4RXFP1TSHR | |
| SCHEMBL28097945 | 0.71 | KDM4E (0.61) | CYP3A4RXFP1EGFR | |
| SCHEMBL10736059 | 0.71 | PDE7A (0.50) | SMN1; SMN2NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4652558-A | FUNGICIDES, INSECTICIDES | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |