Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733741 | 0.80 | DRD4 (0.57) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11590816 | 0.73 | SETD7 (0.42) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3152103 | 0.73 | DRD2 (0.44) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL875920 | 0.73 | DRD2 (0.44) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11589967 | 0.71 | GAA (0.44) | CYP1A2TDP1MAPTCYP2C19HTR2A | |
| SCHEMBL11113950 | 0.70 | SETD7 (0.39) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12070616 | 0.70 | MAPK1 (0.51) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19537683 | 0.69 | MAPK1 (0.57) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| Clopipazan SCHEMBL1816896 | 0.69 | SETD7 (0.76) | DRD4DRD2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11081947 | 0.68 | TSHR (0.40) | DRD4DRD2HRH4HTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209608-A1 | DEUTERIUM-ENRICHED ASENAPINE | PROTIA, LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209608-A1 | DEUTERIUM-ENRICHED ASENAPINE | NSD2, DRD2, SNRPD2 | DRD4 17/4885DRD2 2/4885CYP1A2 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.