Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 2/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD5 | P21918 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733983 | 1.00 | PRKCQ (0.54) | PRKCQPRKCDTSHRHTR1ASLC6A4 | |
| SCHEMBL10574316 | 0.86 | KEAP1 (0.49) | PRKCQPRKCDTSHRHTR1ASLC6A4 | |
| SCHEMBL10574309 | 0.86 | KEAP1 (0.49) | PRKCQPRKCDTSHRHTR1ASLC6A4 | |
| SCHEMBL5243103 | 0.85 | HTR1A (0.58) | TSHRHTR1ASLC6A4LTA4HTDP1 | |
| SCHEMBL10730125 | 0.81 | HRH1 (0.54) | TSHRHTR1ASLC6A4LTA4HTDP1 | |
| SCHEMBL10571481 | 0.80 | HRH1 (0.52) | TSHRHTR1ASLC6A4TDP1HRH1 | |
| SCHEMBL10732389 | 0.79 | DRD2 (0.46) | HTR1ASLC6A4DRD4DRD3DRD2 | |
| SCHEMBL10731734 | 0.79 | DRD2 (0.46) | HTR1ASLC6A4DRD4DRD3DRD2 | |
| SCHEMBL10731740 | 0.79 | DRD2 (0.46) | HTR1ASLC6A4DRD4DRD3DRD2 | |
| SCHEMBL14365449 | 0.79 | LTA4H (0.65) | TSHRLTA4HTDP1HRH1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650811-A | HYPOTENSIVE | ROUSSEL UCLAF (FR) | 1987-03-17 | — | — | US | disclosed |