Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 7/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11336987 | 0.98 | L3MBTL1 (0.51) | L3MBTL1MAOAMAOBCRHR1SIGMAR1 | |
| SCHEMBL10734871 | 0.77 | POLB (0.60) | MAOAMAOBSIGMAR1TMEM97 | |
| SCHEMBL2178931 | 0.77 | MAOA (0.68) | MAOASIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11342344 | 0.76 | SMN1; SMN2 (0.58) | MAOAMAOBSIGMAR1TMEM97KDM4E | |
| SCHEMBL7231784 | 0.74 | ALDH1A1 (0.56) | MAOAMAOBSIGMAR1ALDH1A1 | |
| SCHEMBL4591437 | 0.74 | ALDH1A1 (0.53) | MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL10733638 | 0.74 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL10729859 | 0.74 | ALDH1A1 (0.55) | L3MBTL1MAOAMAOBALDH1A1CXCR4 | |
| SCHEMBL18007045 | 0.74 | L3MBTL1 (0.68) | L3MBTL1SIGMAR1TMEM97KDM4EALDH1A1 | |
| SCHEMBL10729289 | 0.74 | OPRK1 (0.45) | MAOAMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004727-B1 | BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-12 | — | — | EP | claimed |
| US-4645771-A | ANTICOAGULANT | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-24 | — | — | US | disclosed |
| EP-0004727-B1 | BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-12 | — | — | EP | disclosed |
| EP-0004727-A2 | Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-10-17 | — | — | EP | disclosed |