Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663368 | 0.88 | MAPT (0.45) | MAPTPPARAPPARGSMN1; SMN2 | |
| SCHEMBL10658293 | 0.81 | PPARA (0.42) | MAPTPPARAPPARGALDH1A1GPBAR1 | |
| SCHEMBL10661841 | 0.81 | MAPT (0.41) | MAPTPPARAPPARGGPBAR1FFAR4 | |
| SCHEMBL10655912 | 0.80 | KDM4E (0.45) | KMOPPARAPPARGKDM4EALDH1A1 | |
| SCHEMBL10664921 | 0.78 | NPC1 (0.42) | MAPTKDM4EALDH1A1HSD17B10GPBAR1 | |
| SCHEMBL10661218 | 0.77 | MAPT (0.43) | MAPTPPARAPPARG | |
| SCHEMBL10735091 | 0.74 | FFAR4 (0.39) | KMOKDM4EFFAR4 | |
| SCHEMBL10657879 | 0.74 | MAPT (0.39) | MAPTPPARAPPARGALDH1A1GPBAR1 | |
| SCHEMBL10730207 | 0.73 | FFAR4 (0.38) | KMOGPBAR1FFAR4SMN1; SMN2 | |
| SCHEMBL11234752 | 0.73 | FFAR4 (0.61) | MAPTPPARAPPARGFFAR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |