Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.65 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.64 |
| ▸ | CASP3 | P42574 | 10/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 10/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 9/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737504 | 0.83 | DYRK1A (0.66) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL8679222 | 0.81 | MAPT (0.60) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL10736453 | 0.81 | MEN1 (0.71) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL10733695 | 0.80 | DYRK1A (0.68) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL30432 | 0.79 | HSD17B1 (1.00) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL30675318 | 0.78 | PCSK9 (1.00) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL28849849 | 0.78 | PCSK9 (1.00) | SMN1; SMN2MAPTALDH1A1LMNANPC1 | |
| SCHEMBL11663113 | 0.78 | GHSR (0.74) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL11279344 | 0.77 | DYRK1A (1.00) | SMN1; SMN2NPC1RAB9ACASP3SENP7 | |
| SCHEMBL21682009 | 0.77 | CASP3 (0.65) | SMN1; SMN2MAPTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675331-A | INSECTICIDE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-06-23 | — | — | US | disclosed |