SCHEMBL10736722

SCHEMBL10736722

CCOC(O)CCCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.46
FFAR1 O14842 2/20 0.46
AKR1B1 P15121 1/20 0.43
FFAR3 O14843 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
GPR84 Q9NQS5 7/20 0.41
PPARG P37231 7/20 0.41
PPARD Q03181 7/20 0.41
PPARA Q07869 7/20 0.41
HDAC11 Q96DB2 5/20 0.41
TSHR P16473 4/20 0.41
PTPN1 P18031 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TLR2 O60603 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
FABP4 P15090 2/20 0.41
SLC22A6 Q4U2R8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27715501 0.87 GABRP (0.48) FFAR4FFAR1AKR1B1FFAR3HDAC3
SCHEMBL9517412 0.81 AKR1B1 (0.44) FFAR4FFAR1AKR1B1GPR84PPARG
SCHEMBL13869507 0.80 TSHR (0.52) PPARGPPARATSHRALDH1A1MEN1
SCHEMBL7888034 0.79 THRB (0.40) TSHRMEN1KMT2A
SCHEMBL3820500 0.79 GABRP (0.45) FFAR4FFAR1AKR1B1GPR84PPARG
SCHEMBL27961870 0.78 CAMK2A (0.44) FFAR4FFAR1GPR84TSHRALDH1A1
SCHEMBL6385659 0.78 AKR1B1 (0.41) FFAR4FFAR1AKR1B1GPR84PPARG
SCHEMBL8673973 0.78 AKR1B1 (0.41) FFAR4FFAR1AKR1B1GPR84PPARG
SCHEMBL28239013 0.78 PAOX (0.39) FFAR4FFAR1GPR84ALDH1A1
Stearic Acid SCHEMBL27604205 0.77 GPR84 (0.61) FFAR4FFAR1AKR1B1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090130648-A1 Oxidized Phospholipids TECHNISCHE UNIVERSITÄT GRAZ (AT) 2009-05-21 US disclosed
US-4680285-A Treatment of malignant tumors with 2-(β-D-ribofuranosylthiazole-4-carboxamide related compounds VIRATEK, INC. (US) 1987-07-14 US disclosed
EP-0090405-B1 NOVEL AZOLE DINUCLEOTIDE COMPOUNDS AND METHODS FOR THEIR PRODUCTION BRIGHAM YOUNG UNIVERSITY (US) 1986-06-25 EP disclosed
US-4594415-A Viricides ROBINS ROLAND K (US) 1986-06-10 US disclosed
US-4544741-A Azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY, PROVO, UT., A NONPROFIT CORP. OF UT 1985-10-01 US disclosed
EP-0090405-A1 Novel azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY (US) 1983-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090130648-A1 Oxidized Phospholipids SGMS1, SGMS2, PHOSPHO1 FFAR4 964/4885FFAR1 472/4885AKR1B1 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.