Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743662 | 0.86 | LMNA (0.42) | KMT2AMEN1GFERMKNK1MKNK2 | |
| SCHEMBL7957240 | 0.84 | MKNK1 (0.39) | KMT2AMEN1GFERMKNK1MKNK2 | |
| SCHEMBL7957167 | 0.79 | MKNK1 (0.40) | KMT2AMEN1MKNK1MKNK2CSNK1D | |
| SCHEMBL7946510 | 0.78 | CYP11B2 (0.42) | KMT2ALMNACYP1A2CYP3A4CYP11B2 | |
| SCHEMBL7951763 | 0.78 | MEN1 (0.48) | KMT2AMEN1GFERMKNK1MKNK2 | |
| SCHEMBL7953609 | 0.75 | MEN1 (0.53) | KMT2AMEN1GFERCYP11B2RXFP1 | |
| SCHEMBL10736493 | 0.74 | MKNK1 (0.46) | KMT2AMKNK1MKNK2RXFP1PKN1 | |
| Iodide SCHEMBL10859030 | 0.73 | MKNK1 (0.46) | KMT2AMKNK1MKNK2RXFP1PKN1 | |
| SCHEMBL7946516 | 0.70 | NPC1 (0.36) | KMT2AMEN1GFERPOLBCYP1A2 | |
| SCHEMBL10736187 | 0.69 | MKNK1 (0.37) | MKNK1MKNK2LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684658-A | Anti-thrombotic ortho-condensed pyrrole derivatives, compositions, and method of use therefor | RHONE-POULENC SANTE (FR) | 1987-08-04 | — | — | US | claimed |
| US-4684658-A | Anti-thrombotic ortho-condensed pyrrole derivatives, compositions, and method of use therefor | RHONE-POULENC SANTE (FR) | 1987-08-04 | — | — | US | disclosed |