Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739731 | 0.93 | L3MBTL1 (0.37) | L3MBTL1LMNATTRMAPTATM | |
| SCHEMBL10739757 | 0.91 | VDR (0.34) | VDRFFAR4FFAR1L3MBTL1LMNA | |
| SCHEMBL10546364 | 0.90 | CALM1 (0.44) | TTR | |
| SCHEMBL10547822 | 0.90 | FFAR1 (0.38) | FFAR1L3MBTL1TTRMAPTATM | |
| SCHEMBL10547396 | 0.90 | MAPT (0.36) | L3MBTL1LMNATTRMAPTATM | |
| SCHEMBL393264 | 0.89 | LTA4H (0.43) | L3MBTL1LMNAMAPTATMPPARG | |
| SCHEMBL10547659 | 0.88 | TTR (0.34) | VDRTTRPPARGPPARDPPARA | |
| SCHEMBL10549307 | 0.88 | L3MBTL1 (0.40) | L3MBTL1PPARG | |
| SCHEMBL10548739 | 0.87 | PPARG (0.36) | TTRPPARGPPARDPPARA | |
| SCHEMBL10543680 | 0.86 | TTR (0.36) | TTRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |