Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.39 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944135 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10731544 | 0.90 | HSPA5 (0.42) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10730710 | 0.90 | HSPA5 (0.44) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10660829 | 0.90 | HSPA5 (0.44) | ALDH1A1TDP1KDM4EHSPA5MEN1 | |
| SCHEMBL10660936 | 0.89 | CYP1A2 (0.43) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10945766 | 0.87 | KDM4E (0.44) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10665892 | 0.82 | NPC1 (0.45) | ALDH1A1TDP1NPC1RAB9AKDM4E | |
| SCHEMBL10943621 | 0.81 | PTGS2 (0.37) | L3MBTL1 | |
| SCHEMBL10737795 | 0.81 | MEN1 (0.42) | ALDH1A1TDP1NPC1RAB9AHSPA5 | |
| SCHEMBL10946172 | 0.79 | P2RX7 (0.38) | ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687857-A | Alkyl β-oxo-benzenepropanoates | Uclaf, Roussel (FR) | 1987-08-18 | — | — | US | disclosed |
| US-4518775-A | Benzoxazine-4-one intermediates | ROUSSEL UCLAF (FR) | 1985-05-21 | — | — | US | disclosed |
| US-4397856-A | Analgesic 4-hydroxy-3-quinolinecarboxamides | ROUSSEL UCLAF (FR) | 1983-08-09 | — | — | US | disclosed |