Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944127 | 0.91 | MEN1 (0.41) | MEN1KMT2AL3MBTL1HPGDNPC1 | |
| SCHEMBL10730705 | 0.91 | HSPA5 (0.43) | MEN1KMT2AL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL10731537 | 0.91 | HTT (0.42) | MEN1KMT2AL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL10660799 | 0.91 | HSPA5 (0.43) | MEN1KMT2AL3MBTL1HPGDFFAR2 | |
| SCHEMBL10660913 | 0.90 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1HPGDNPC1 | |
| SCHEMBL10945755 | 0.89 | MEN1 (0.44) | MEN1KMT2AL3MBTL1HPGDNPC1 | |
| SCHEMBL10665874 | 0.84 | NPC1 (0.48) | MEN1KMT2AL3MBTL1HPGDNPC1 | |
| SCHEMBL10743173 | 0.82 | METAP1 (0.41) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL10743968 | 0.81 | HTT (0.47) | L3MBTL1HPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10744566 | 0.81 | HSPA5 (0.49) | MEN1KMT2AHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687857-A | Alkyl β-oxo-benzenepropanoates | Uclaf, Roussel (FR) | 1987-08-18 | — | — | US | disclosed |
| US-4518775-A | Benzoxazine-4-one intermediates | ROUSSEL UCLAF (FR) | 1985-05-21 | — | — | US | disclosed |
| US-4397856-A | Analgesic 4-hydroxy-3-quinolinecarboxamides | ROUSSEL UCLAF (FR) | 1983-08-09 | — | — | US | disclosed |