Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797870 | 0.87 | ALDH1A1 (0.58) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL11731976 | 0.87 | TDP1 (0.52) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL17797886 | 0.85 | ALDH1A1 (0.56) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL10434629 | 0.84 | CA1 (0.46) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL132053 | 0.84 | LMNA (0.67) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL18819 | 0.83 | CA1 (0.62) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL2473943 | 0.82 | LMNA (0.70) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| Acetic Acid SCHEMBL27352564 | 0.82 | LMNA (0.55) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL10352997 | 0.82 | TSHR (0.55) | SMN1; SMN2LMNATSHRESR1ALDH1A1 | |
| SCHEMBL8674165 | 0.82 | CA1 (0.60) | SMN1; SMN2LMNATSHRESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |