Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3540500 | 0.71 | HTR6 (0.45) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL21086633 | 0.71 | ALDH1A1 (0.44) | KMT2AMEN1HSD17B10TDP1RAB9A | |
| SCHEMBL3531433 | 0.70 | GCK (0.52) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL11887704 | 0.68 | RAB9A (0.75) | KMT2AMEN1HPGDHSD17B10TP53 | |
| SCHEMBL38665218 | 0.68 | MEN1 (0.53) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL17961164 | 0.68 | SMN1; SMN2 (0.52) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL28763698 | 0.67 | EHMT2 (0.48) | KMT2AMEN1HSD17B10TDP1NPC1 | |
| SCHEMBL10739013 | 0.67 | KMT2A (0.38) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL8938457 | 0.66 | LPO (0.48) | KMT2AMEN1HPGDKDM4EHSD17B10 | |
| SCHEMBL15381506 | 0.65 | EHMT2 (0.45) | KMT2AMEN1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4694015-A | TREATING DREPANOCYTOSIS, MALARIA, AND BABEBIOSIS | SANOFI (FR) | 1987-09-15 | — | — | US | claimed |
| US-4694015-A | TREATING DREPANOCYTOSIS, MALARIA, AND BABEBIOSIS | SANOFI (FR) | 1987-09-15 | — | — | US | disclosed |