Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739911 | 0.87 | KDM4E (0.39) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL10739337 | 0.85 | KDM4E (0.40) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL10736825 | 0.83 | MAPT (0.41) | ALDH1A1MAPTNPC1RAB9ATP53 | |
| SCHEMBL10732219 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4ENPC1HSD17B10 | |
| SCHEMBL10731503 | 0.79 | RAB9A (0.40) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL10734461 | 0.79 | KDM4E (0.42) | ALDH1A1HPGDMAPTKDM4ENPC1 | |
| SCHEMBL10961196 | 0.78 | HSP90AA1 (0.38) | KDM4ENPC1HSD17B10RAB9AOPRD1 | |
| SCHEMBL30554002 | 0.75 | LMNA (0.48) | NPC1RAB9ATP53SMN1; SMN2OPRD1 | |
| SCHEMBL30554022 | 0.73 | SMN1; SMN2 (0.50) | NPC1RAB9ATP53MEN1KMT2A | |
| SCHEMBL28415984 | 0.72 | SMN1; SMN2 (0.47) | NPC1RAB9ATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686219-A | 11-(Piperazin- or homopiperazin-1-yl)-5H-imidazo-(2,1-C)(1,4)benzodiazepines useful as anti-allergics | BOEHRINGER INGELHEIM KG (DE) | 1987-08-11 | — | — | US | disclosed |