Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889760 | 0.85 | MEN1 (0.43) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL10356410 | 0.81 | ESR1 (0.37) | ESR1ESR2ARACHECNR1 | |
| SCHEMBL10786833 | 0.79 | MAOB (0.44) | ESR1ARLMNASLC6A2SLC6A3 | |
| SCHEMBL19843843 | 0.76 | ESR1 (0.62) | ESR1ESR2ARACHETSHR | |
| SCHEMBL10877318 | 0.75 | EBP (0.57) | ESR1ARACHESLC6A2SLC6A4 | |
| SCHEMBL10797608 | 0.73 | ESR1 (0.43) | ESR1ESR2ACHE | |
| SCHEMBL28447541 | 0.72 | MEN1 (0.43) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL10364768 | 0.70 | SMN1; SMN2 (0.41) | ESR1ESR2ARALDH1A1GAA | |
| SCHEMBL10598204 | 0.70 | ESR1 (0.57) | ESR1ESR2ARTSHRALDH1A1 | |
| SCHEMBL10784573 | 0.69 | ESR1 (0.44) | ESR1ESR2ARALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593047-A | Alcoholism | RICHTER GEDEON VEGYESZETI CYAR RT (HU) | 1986-06-03 | — | — | US | disclosed |
| US-4593047-A | Alcoholism | RICHTER GEDEON VEGYESZETI CYAR RT (HU) | 1986-06-03 | — | — | US | disclosed |