⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174030 | 0.97 | — | — | |
| SCHEMBL8556928 | 0.94 | ALDH1A1 (0.39) | — | |
| SCHEMBL3332189 | 0.91 | — | — | |
| SCHEMBL8628650 | 0.88 | ALDH1A1 (0.39) | — | |
| SCHEMBL3923327 | 0.88 | ALDH1A1 (0.39) | — | |
| SCHEMBL3923662 | 0.88 | ALDH1A1 (0.39) | — | |
| SCHEMBL9444828 | 0.88 | ALDH1A1 (0.39) | — | |
| SCHEMBL8167936 | 0.88 | — | — | |
| SCHEMBL31151133 | 0.86 | THRB (0.39) | — | |
| SCHEMBL9579658 | 0.84 | THRB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119135-A | Rigid bridged metallocene-fluorene metal compound and preparation method thereof | 浙江昇茂催化技术有限公司 | 2024-12-13 | — | — | CN | claimed |
| WO-2024087613-A1 | HEPTAFLUOROISOPROPYL-CONTAINING BISAMIDE COMPOUND AND INTERMEDIATE COMPOUND THEREOF, AND PREPARATION METHODS THEREFOR AND USE THEREOF | 浙江宇龙药业有限公司 | 2024-05-02 | — | — | WO | claimed |
| CN-115974717-A | Heptafluoroisopropyl-containing bisamide compound and intermediate compound thereof, and preparation method and application thereof | 浙江宇龙药业有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-12435060-B2 | Acylamino bridged heterocyclic compound, and composition and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| EP-4610251-A1 | HEPTAFLUOROISOPROPYL-CONTAINING BISAMIDE COMPOUND AND INTERMEDIATE COMPOUND THEREOF, AND PREPARATION METHODS THEREFOR AND USE THEREOF | Zhejiang Udragon Pesticides And Chemicals Co., Ltd. (CN) | 2025-09-03 | — | — | EP | disclosed |
| CN-116947679-B | Bisamide compound containing sevoflurane isopropyl, and preparation method and application thereof | 浙江宇龙药业有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119119135-A | Rigid bridged metallocene-fluorene metal compound and preparation method thereof | 浙江昇茂催化技术有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119340-A | Olefin polymer and preparation method thereof | 浙江昇茂催化技术有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-3577118-B1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | GILEAD SCIENCES INC (US) | 2024-09-04 | — | — | EP | disclosed |
| EP-3901147-B1 | ACYLAMINO BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | disclosed |
| CN-116947679-A | Bisamide compound containing sevoflurane isopropyl, and preparation method and application thereof | 浙江宇龙药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-0159677-B1 | NOVEL 4,5-BIS(4-METHOXYPHENYL)-2-(PYRROL-2-YL)THIAZOLES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KANEBO, LTD. (JP) | 1989-02-22 | — | — | EP | disclosed |
| US-4659726-A | ANTICOAGULANTS | KANEBO, LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0159677-A2 | Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |
| US-4235820-A | Process for dibenzocycloheptene compounds | MERCK & CO., INC. (US) | 1980-11-25 | — | — | US | disclosed |
| US-4048223-A | 3-Dimethylsulfamoyl-5-[amino(alkyl or alkylidene)]-5H-dibenzo [a,d]cycloheptenes | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4014895-A | Method for synthesis of optically active thiolactones | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-29 | — | — | US | disclosed |
| US-3981917-A | Chemical compounds | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3972936-A | ANTIDEPRESSANT | MERCK & CO., INC. (US) | 1976-08-03 | — | — | US | disclosed |