Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923327 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL8167936 | 1.00 | — | — | |
| SCHEMBL9444828 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL3923662 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL3332189 | 0.97 | — | — | |
| SCHEMBL9579658 | 0.95 | THRB (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL15922787 | 0.95 | MEN1 (0.38) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL6151432 | 0.95 | THRB (0.43) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL31151133 | 0.92 | THRB (0.39) | ALDH1A1HTTMEN1THRBKMT2A | |
| SCHEMBL1074128 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222353-A1 | MACROCYCLIC INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| US-11124617-B2 | Materials coated with calixarenes | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2021-09-21 | — | — | US | disclosed |
| EP-2836539-B1 | MATERIALS COATED WITH CALIXARENES | UNIV LIBRE DE BRUXELLES ULB (BE) | 2019-09-18 | — | — | EP | disclosed |
| US-20190233358-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2019-08-01 | — | — | US | disclosed |
| US-10329232-B2 | Materials coated with calixarenes | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2019-06-25 | — | — | US | disclosed |
| CN-108793174-A | A kind of meso-porous titanium dioxide silica fibre and preparation method thereof | 江南大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-104487496-A | Materials coated with calixarenes | UNIV LIBRE DE BRUXELLES ULB | 2015-04-01 | — | — | CN | disclosed |
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITÉ PARIS CITÉ (FR) | 2015-03-05 | — | — | US | disclosed |
| EP-2836539-A1 | MATERIALS COATED WITH CALIXARENES | Université Libre de Bruxelles (ULB) (BE) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013152967-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2013-10-17 | — | — | WO | disclosed |
| EP-0666847-B1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | ALLELIX BIOPHARMA (CA) | 1998-06-17 | — | — | EP | disclosed |
| US-5496957-A | 5-HYDOXYTRYPTAMINE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0504812-B1 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL CO (JP) | 1995-09-06 | — | — | EP | disclosed |
| EP-0666847-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | Allelix Biopharmaceuticals Inc. (CA) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006638-A1 | TRYPTAMINE ANALOGS WITH 5-HT1D SELECTIVITY | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1995-03-09 | — | — | WO | disclosed |
| US-5302619-A | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-12 | — | — | US | disclosed |
| US-5262441-A | APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5223232-A | Solvent extraction of solutions from irradiated nuclear fuel reprocessing plants | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-06-29 | — | — | US | disclosed |
| EP-0504812-A2 | Aromatic compounds, their production processes and their compositions for the control of insect pests | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124617-B2 | Materials coated with calixarenes | CALD1, CALU, CALR | ALDH1A1 1356/4885HTT 4103/4885MEN1 4566/4885 |
| US-10329232-B2 | Materials coated with calixarenes | CALU, CALD1, CALR | ALDH1A1 1645/4885HTT 4476/4885MEN1 4791/4885 |
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | ALDH1A1 1356/4885HTT 4103/4885MEN1 4566/4885 |
| US-20190233358-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | ALDH1A1 1356/4885HTT 4103/4885MEN1 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.