Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSPA2 | P54652 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743968 | 0.92 | HTT (0.47) | METAP1HSPA5HSPA2HTTSMN1; SMN2 | |
| SCHEMBL10744566 | 0.90 | HSPA5 (0.49) | METAP1HSPA5MEN1KMT2AHSPA2 | |
| SCHEMBL10739363 | 0.88 | METAP1 (0.43) | METAP1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10740057 | 0.87 | HSPA5 (0.51) | HSPA5MEN1KMT2AHSPA2HSPA9 | |
| SCHEMBL10738767 | 0.85 | CTSS (0.46) | HSPA5MEN1KMT2AHSPA2HSPA9 | |
| SCHEMBL10944127 | 0.83 | MEN1 (0.41) | HSPA5MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL10660799 | 0.83 | HSPA5 (0.43) | HSPA5MEN1KMT2AHSPA2HTT | |
| SCHEMBL10731537 | 0.83 | HTT (0.42) | HSPA5MEN1KMT2AHSPA2HTT | |
| SCHEMBL10730705 | 0.83 | HSPA5 (0.43) | HSPA5MEN1KMT2AHSPA2HTT | |
| SCHEMBL10737795 | 0.82 | MEN1 (0.42) | HSPA5MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636512-A | Anti-inflammatory 2-substituted-4-hydroxy-3-quinoline carboxamides | ROUSSEL UCLAF (FR) | 1987-01-13 | — | — | US | disclosed |