Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.40 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731537 | 0.91 | HTT (0.42) | HSPA5MEN1KMT2AHPGDHTT | |
| SCHEMBL10737795 | 0.91 | MEN1 (0.42) | HSPA5MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10660799 | 0.89 | HSPA5 (0.43) | HSPA5MEN1KMT2AHPGDHTT | |
| SCHEMBL10944127 | 0.88 | MEN1 (0.41) | HSPA5MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10660913 | 0.86 | ALDH1A1 (0.43) | HSPA5MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL10945755 | 0.85 | MEN1 (0.44) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10743968 | 0.83 | HTT (0.47) | HSPA5HPGDHTTSMN1; SMN2HSPA9 | |
| SCHEMBL10665874 | 0.83 | NPC1 (0.48) | MEN1KMT2AHPGDSMN1; SMN2L3MBTL1 | |
| SCHEMBL10732199 | 0.83 | PKM (0.45) | HSPA5HPGDHTTSMN1; SMN2HSPA9 | |
| SCHEMBL10743173 | 0.83 | METAP1 (0.41) | HSPA5MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687857-A | Alkyl β-oxo-benzenepropanoates | Uclaf, Roussel (FR) | 1987-08-18 | — | — | US | disclosed |