Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 3/20 | 0.43 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737795 | 0.91 | MEN1 (0.42) | HSPA5FFAR2MEN1KMT2AHPGD | |
| SCHEMBL10731537 | 0.89 | HTT (0.42) | HSPA5HSPA2FFAR2MEN1KMT2A | |
| SCHEMBL10730705 | 0.89 | HSPA5 (0.43) | HSPA5HSPA2MEN1KMT2AHPGD | |
| SCHEMBL10944127 | 0.88 | MEN1 (0.41) | HSPA5MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL10660913 | 0.86 | ALDH1A1 (0.43) | HSPA5HSPA2MEN1KMT2AHPGD | |
| SCHEMBL10945755 | 0.85 | MEN1 (0.44) | FFAR2MEN1KMT2AHPGDL3MBTL1 | |
| SCHEMBL10744566 | 0.85 | HSPA5 (0.49) | HSPA5HSPA2MEN1KMT2AALOX15 | |
| SCHEMBL10731555 | 0.83 | PKM (0.46) | HSPA5HSPA2FFAR2HPGDPKM | |
| SCHEMBL10665874 | 0.83 | NPC1 (0.48) | MEN1KMT2AHPGDL3MBTL1PKM | |
| SCHEMBL10743173 | 0.83 | METAP1 (0.41) | HSPA5HSPA2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736033-A | Certain 1,3-dihydro-1-[heterocyclic)imino]-furo-[3,4-b]quinoline 9-ol compounds having analgesic and anti-inflammatory activity | ROUSSEL UCLAF (FR) | 1988-04-05 | — | — | US | disclosed |
| US-4596875-A | Reacting benzoxazole compound with amide to decyclize, cyclizing to form quinoline derivative | ROUSSEL UCLAF (FR) | 1986-06-24 | — | — | US | disclosed |
| US-4486438-A | 4-Hydroxy-3-quinoline-carboxylic acid derivatives | ROUSSEL UCLAF (FR) | 1984-12-04 | — | — | US | disclosed |