Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967217 | 0.90 | ADRB2 (0.54) | ADRB2ADRB1ADRB3USP2CYP1A2 | |
| SCHEMBL10737298 | 0.88 | ADRB2 (0.58) | ADRB2ADRB1ADRB3MEN1USP2 | |
| SCHEMBL10743558 | 0.84 | CYP1A2 (0.60) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL10738067 | 0.84 | ADRB2 (0.78) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10965217 | 0.81 | NR2E1 (0.80) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11225584 | 0.80 | ADRB2 (0.63) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL11207616 | 0.80 | HTR1A (0.67) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10746452 | 0.79 | CYP2D6 (0.77) | ADRB2ADRB1ADRB3MEN1HTT | |
| SCHEMBL22640075 | 0.78 | MAPT (0.68) | ADRB2ADRB1ADRB3MEN1USP2 | |
| SCHEMBL11201568 | 0.78 | MAPT (0.68) | ADRB2ADRB1ADRB3MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711887-A | HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-08 | — | — | US | disclosed |