Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747245 | 1.00 | TBXA2R (0.57) | TBXA2RMTNR1BLMNAMAPTNPSR1 | |
| SCHEMBL10341099 | 0.87 | TBXA2R (0.53) | TBXA2RMTNR1BLMNAMAPTNPSR1 | |
| SCHEMBL10341096 | 0.87 | TBXA2R (0.53) | TBXA2RMTNR1BLMNAMAPTNPSR1 | |
| SCHEMBL8199189 | 0.81 | DRD2 (0.71) | TBXA2RLMNADRD1ADRB2ADRB1 | |
| SCHEMBL10108786 | 0.78 | TBXA2R (0.61) | TBXA2RLMNADRD1ADRB2ADRB1 | |
| SCHEMBL9025225 | 0.73 | HCRTR1 (0.51) | MTNR1BLMNAMAPTNPSR1CYP3A4 | |
| SCHEMBL9416632 | 0.73 | DRD2 (0.72) | MTNR1BLMNAMAPTNPSR1DRD1 | |
| SCHEMBL6318855 | 0.72 | MTNR1B (1.00) | MTNR1B | |
| SCHEMBL328651 | 0.71 | DRD2 (0.69) | MTNR1BDRD1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3506766 | 0.71 | MTNR1B (0.69) | MTNR1BDRD1CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4678853-A | ADENYLATE CYCLASE INHIBITORS | T P O "PHARMACHIM" (BG) | 1987-07-07 | — | — | US | claimed |
| US-4678853-A | ADENYLATE CYCLASE INHIBITORS | T P O "PHARMACHIM" (BG) | 1987-07-07 | — | — | US | disclosed |