Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741661 | 0.91 | MAPT (0.53) | L3MBTL1CFTRALDH1A1MAPTHTT | |
| SCHEMBL10747092 | 0.89 | CFTR (0.48) | L3MBTL1CFTRALDH1A1MAPTHTT | |
| SCHEMBL10741387 | 0.88 | L3MBTL1 (0.47) | L3MBTL1CFTRALDH1A1MAPTHTT | |
| SCHEMBL10740889 | 0.88 | MAPT (0.49) | L3MBTL1CFTRMAPTHTTNPSR1 | |
| SCHEMBL10746093 | 0.87 | LRRK2 (0.48) | L3MBTL1CFTRKMT2AMAPTHTT | |
| SCHEMBL10746094 | 0.85 | FKBP1A (0.53) | L3MBTL1KMT2AALDH1A1HPGDKCNQ3 | |
| SCHEMBL11821280 | 0.84 | FKBP1A (0.52) | L3MBTL1KMT2AALDH1A1HPGDKCNQ3 | |
| SCHEMBL11819040 | 0.84 | FKBP1A (0.52) | L3MBTL1KMT2AALDH1A1HPGDKCNQ3 | |
| SCHEMBL11825095 | 0.84 | FKBP1A (0.52) | L3MBTL1KMT2AALDH1A1HPGDKCNQ3 | |
| SCHEMBL11821844 | 0.84 | FKBP1A (0.52) | L3MBTL1KMT2AALDH1A1HPGDKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |