Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740889 | 0.89 | MAPT (0.49) | CFTRL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10745596 | 0.89 | L3MBTL1 (0.49) | CFTRL3MBTL1PPARDPPARAPPARG | |
| SCHEMBL10741387 | 0.87 | L3MBTL1 (0.47) | CFTRL3MBTL1CYP1A2CYP3A4ALPG | |
| SCHEMBL10741661 | 0.85 | MAPT (0.53) | CFTRL3MBTL1CYP1A2CYP3A4ALPG | |
| SCHEMBL10744540 | 0.82 | CFTR (0.47) | CFTRL3MBTL1CYP1A2CYP3A4ALPG | |
| SCHEMBL10746093 | 0.81 | LRRK2 (0.48) | CFTRL3MBTL1CYP1A2CYP3A4ALPG | |
| SCHEMBL17080116 | 0.79 | KDM4E (0.46) | L3MBTL1CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10744475 | 0.78 | PPARD (0.49) | L3MBTL1SMN1; SMN2PPARDPPARAPPARG | |
| SCHEMBL11773094 | 0.75 | RAB9A (0.49) | CFTRCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL17080148 | 0.74 | KDM4E (0.56) | L3MBTL1CYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663344-A | ANTIPYRETICS, ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1987-05-05 | — | — | US | disclosed |