Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.64 |
| ▸ | CMA1 | P23946 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362594 | 0.91 | TACR1 (0.67) | TACR1OPRM1OPRD1OPRK1 | |
| SCHEMBL10364251 | 0.88 | TACR1 (0.57) | TACR1CMA1 | |
| SCHEMBL10364533 | 0.80 | ITGB3 (0.58) | TACR1 | |
| SCHEMBL30157193 | 0.80 | OPRM1 (0.73) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10363304 | 0.79 | TACR1 (0.52) | TACR1CMA1 | |
| SCHEMBL3635117 | 0.79 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10362638 | 0.79 | TACR1 (0.57) | TACR1 | |
| SCHEMBL30157177 | 0.78 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL38658663 | 0.78 | OPRM1 (0.78) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10362832 | 0.77 | TACR1 (0.53) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |