Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288450 | 0.91 | EPHX1 (0.47) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL9013764 | 0.89 | CYP1A2 (0.47) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL10519718 | 0.88 | HRH4 (0.52) | CPA1CTNNB1HRH4TDP1 | |
| SCHEMBL7291238 | 0.88 | HRH4 (0.52) | CPA1CTNNB1HRH4TDP1 | |
| SCHEMBL7291021 | 0.86 | KMT2A (0.57) | CTNNB1HRH4 | |
| SCHEMBL10520925 | 0.86 | KMT2A (0.57) | CTNNB1HRH4 | |
| SCHEMBL8006913 | 0.84 | MME (0.47) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL10520573 | 0.84 | MEN1 (0.53) | CTNNB1HRH4MMP2MMP9MMP8 | |
| SCHEMBL10338654 | 0.83 | CPA1 (0.57) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL9194477 | 0.83 | CPA1 (0.57) | MMEACECPA1ACE2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656269-A | RENIN INHIBITORY EFFECT WHEN ADMINISTERING ORALLY; HYPOTENSIVE AGENTS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
| EP-0200406-A2 | Novel amino acid derivatives | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-11-05 | — | — | EP | disclosed |