Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288450 | 0.93 | EPHX1 (0.47) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL10749706 | 0.89 | MME (0.49) | MMEACECPA1ACE2CTNNB1 | |
| SCHEMBL7291021 | 0.85 | KMT2A (0.57) | HPGDCTNNB1HRH4PTPN1CASP1 | |
| SCHEMBL10520925 | 0.85 | KMT2A (0.57) | HPGDCTNNB1HRH4PTPN1CASP1 | |
| SCHEMBL7291238 | 0.83 | HRH4 (0.52) | HPGDCPA1CTNNB1HRH4 | |
| SCHEMBL10519718 | 0.83 | HRH4 (0.52) | HPGDCPA1CTNNB1HRH4 | |
| SCHEMBL8006913 | 0.79 | MME (0.47) | HPGDMMEACECPA1ACE2 | |
| SCHEMBL10520573 | 0.79 | MEN1 (0.53) | HPGDCTNNB1HRH4MMP2MMP9 | |
| SCHEMBL10519877 | 0.78 | AANAT (0.57) | CYP1A2CYP3A4CYP2C19MMP9 | |
| SCHEMBL3814684 | 0.78 | CTNNB1 (0.56) | CYP1A2MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745584-A1 | Arylalkyl(thio) carboxamides compounds with affinity for melatonine receptors, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |