Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572365 | 0.85 | ALDH1A1 (0.48) | HTTALDH1A1SMN1; SMN2HSD11B1POLB | |
| SCHEMBL163836 | 0.85 | ALDH1A1 (0.48) | HTTALDH1A1SMN1; SMN2HSD11B1POLB | |
| SCHEMBL13994214 | 0.84 | HCRTR2 (0.36) | KDM4EHTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15461580 | 0.81 | EPAS1 (0.45) | — | |
| SCHEMBL168868 | 0.80 | SLC22A12 (0.38) | KDM4ETSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29572421 | 0.80 | SLC22A12 (0.38) | KDM4ETSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL27930056 | 0.79 | ALDH1A1 (0.33) | L3MBTL1HTTTDP1TSHRALDH1A1 | |
| SCHEMBL14568177 | 0.78 | ALDH1A1 (0.46) | KDM4ECYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL11083190 | 0.78 | HTT (0.46) | KDM4ECYP1A2CYP2C19L3MBTL1HTT | |
| SCHEMBL646910 | 0.78 | TRPV4 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | claimed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | claimed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | claimed |
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2268615-B1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| US-8445689-B2 | Pesticides | DOW AGROSCIENCES, LLC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120225782-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2012-09-06 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178685-B2 | Pesticides | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110077160-A1 | PESTICIDES | DOW AGROSCIENCES LLC | 2011-03-31 | — | — | US | disclosed |
| EP-2268615-A1 | PESTICIDES | Dow AgroSciences LLC (US) | 2011-01-05 | — | — | EP | disclosed |
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009111309-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090221424-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-03 | — | — | US | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | KDM4E 706/4885CYP1A2 40/4885CYP2C19 164/4885 |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 1172/4885CYP1A2 557/4885CYP2C19 1660/4885 |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 1172/4885CYP1A2 557/4885CYP2C19 1660/4885 |
| US-20120225782-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KDM4E 2245/4885CYP1A2 64/4885CYP2C19 42/4885 |
| US-20090221424-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KDM4E 2251/4885CYP1A2 64/4885CYP2C19 40/4885 |
| US-20110077160-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KDM4E 2251/4885CYP1A2 64/4885CYP2C19 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.