Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 10/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461580 | 0.85 | EPAS1 (0.45) | TRPV4EPAS1SLC22A12PTGES2ELANE | |
| SCHEMBL168370 | 0.81 | SLC22A12 (0.40) | EPAS1SLC22A12PTGES2MAPT | |
| SCHEMBL29572365 | 0.81 | ALDH1A1 (0.48) | EPAS1SLC22A12 | |
| SCHEMBL163836 | 0.81 | ALDH1A1 (0.48) | EPAS1SLC22A12 | |
| SCHEMBL29572114 | 0.81 | SLC22A12 (0.40) | EPAS1SLC22A12PTGES2MAPT | |
| SCHEMBL29572421 | 0.81 | SLC22A12 (0.38) | TRPV4EPAS1SLC22A12PTGES2 | |
| SCHEMBL168868 | 0.81 | SLC22A12 (0.38) | TRPV4EPAS1SLC22A12PTGES2 | |
| SCHEMBL13994240 | 0.80 | EPAS1 (0.37) | TRPV4EPAS1SLC22A12PTGES2MAPT | |
| SCHEMBL8009725 | 0.80 | KCNN4 (0.37) | EPAS1MAPT | |
| SCHEMBL3247679 | 0.80 | NPC1 (0.49) | TRPV4EPAS1SLC22A12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2500340-A1 | 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides | Syngenta Participations AG. (CH) | 2012-09-19 | — | — | EP | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265579-A2 | 2-CYANOBENZENSULFONAMIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009092590-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-30 | — | — | WO | disclosed |
| US-7563921-B2 | 2-cyano-3(halo)alkoxy-benzenesulfonamide compounds for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2009-07-21 | — | — | US | disclosed |
| US-7544637-B2 | 2-cyano-3(halo)alkoxy-benzenesulfonamide compounds for combating animal pests | BASF AKTIENGESELLSCHAFT (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20080306297-A1 | NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080063678-A1 | Novel 2-Cyano-3(Halo)Alkoxy-Benzenesulfonamide Compounds for Combating Animal Pests | BASF AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | US | disclosed |
| WO-2007093530-A1 | THIOAMIDE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-08-23 | — | — | WO | disclosed |
| EP-1819668-A2 | NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056433-A2 | NOVEL 2-CYANO-3-(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | TRPV4 1808/4885EPAS1 3783/4885SLC22A12 1783/4885 |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CYCS | TRPV4 2083/4885EPAS1 4590/4885SLC22A12 3138/4885 |
| US-20080306297-A1 | NOVEL 2-CYANO-3(HALO)ALKOXY-BENZENESULFONAMIDE COMPOUNDS FOR COMBATING ANIMAL PESTS | CBR3, CNPY3, CNPY2 | TRPV4 1423/4885EPAS1 3231/4885SLC22A12 1564/4885 |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CCNY | TRPV4 2727/4885EPAS1 4660/4885SLC22A12 3878/4885 |
| US-20080063678-A1 | Novel 2-Cyano-3(Halo)Alkoxy-Benzenesulfonamide Compounds for Combating Animal Pests | CNPY2, CNPY3, CBR3 | TRPV4 1839/4885EPAS1 3624/4885SLC22A12 1276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.