SCHEMBL258224

SCHEMBL258224

O=C(O)c1cnccc1Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 9/20 0.59
FTO Q9C0B1 2/20 0.59
KDM5B Q9UGL1 2/20 0.59
ALKBH2 Q6NS38 1/20 0.59
ALKBH3 Q96Q83 1/20 0.59
KDM2A Q9Y2K7 1/20 0.59
KDM3A Q9Y4C1 1/20 0.59
KDM4C Q9H3R0 11/20 0.53
KDM4D Q6B0I6 5/20 0.53
KDM4E B2RXH2 2/20 0.53
KDM4A O75164 2/20 0.53
TSHR P16473 1/20 0.51
PTPN1 P18031 3/20 0.49
PTPN2 P17706 1/20 0.49
PTPN6 P29350 1/20 0.49
EGLN3 Q9H6Z9 1/20 0.48
USP2 O75604 1/20 0.47
CYP11B1 P15538 1/20 0.45
CYP11B2 P19099 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11628317 0.90 NAPRT (0.53) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL9870441 0.87 FTO (0.56) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL4951259 0.86 KDM4C (0.56) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL10751618 0.85 KDM4C (0.56) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL10339391 0.84 KDM6B (0.49) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL6491004 0.83 FTO (0.56) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL9868870 0.83 FTO (0.53) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL9870443 0.83 FTO (0.52) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL17737239 0.81 TSHR (0.67) KDM6BFTOKDM5BALKBH2ALKBH3
SCHEMBL7109229 0.81 FTO (0.51) KDM6BFTOKDM5BALKBH2ALKBH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-3453364-B1 HEAT GENERATOR KOBAYASHI PHARMACEUTICAL CO LTD (JP) 2022-08-24 EP claimed
WO-2007046577-A1 EXTERNAL COMPOSITION FOR HAIR GROWTH AMOREPACIFIC CORPORATION (KR) 2007-04-26 WO claimed
US-7081258-B2 Composition for promoting hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2006-07-25 US claimed
US-20260041109-A1 ROBUST FLAVOR EMULSIONS INT FLAVORS & FRAGRANCES INC (US) 2026-02-12 US disclosed
US-20250297398-A1 METHOD FOR DEPOSITING A ZINC-NICKEL ALLOY ON A SUBSTRATE, AN AQUEOUS ZINC-NICKEL DEPOSITION BATH, A BRIGHTENING AGENT AND USE THEREOF Atotech Deutschland GmbH & Co. KG (DE) 2025-09-25 US disclosed
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US disclosed
EP-4615958-A1 CELL COMPOSITIONS Givaudan SA (CH) 2025-09-17 EP disclosed
US-12357547-B2 Compositions containing microcapsules INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-07-15 US disclosed
US-12324452-B2 Delivery systems and methods of preparing the same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-06-10 US disclosed
EP-4561360-A1 ROBUST FLAVOR EMULSIONS International Flavors & Fragrances Inc. (US) 2025-06-04 EP disclosed
US-12274771-B2 Polyurea capsule compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-04-15 US disclosed
EP-1435899-A1 A COMPOSITION FOR PROMOTING HAIR GROWTH LG Household & Health Care Ltd. (KR) 2004-07-14 EP disclosed
US-20040063794-A1 Vehicle for topical delivery of anti-inflammatory compounds ALPHARX INC. (CA) 2004-04-01 US disclosed
EP-1089704-B1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 2004-02-11 EP disclosed
WO-2003041669-A1 A COMPOSITION FOR PROMOTING HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2003-05-22 WO disclosed
US-6479059-B2 A COSMETIC COMPOSITION TO REACTIVATE THE PHYSIOLOGICAL GROWTH OF HAIR; COMPRISING A SYNERGISTIC MIXTURE OF CYSTEINE OR DERIVATIVES, LYSINE OR DERIVATIVES AND A GLYCOPROTEIN IN A CARRIER; SIDE EFFECT REDUCTION; THICKENING GROWTH GECOMWERT ANSTALT (LI) 2002-11-12 US disclosed
US-20010003583-A1 Trichological lotion for topical use GECOMWERT ANSTALT 2001-06-14 US disclosed
EP-1089704-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE Gecomwert Anstalt (LI) 2001-04-11 EP disclosed
WO-1999066887-A1 TRICHOLOGICAL LOTION FOR TOPICAL USE GECOMWERT ANSTALT (LI) 1999-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357547-B2 Compositions containing microcapsules COPE, SAAL1, AUP1 KDM6B 4480/4885FTO 2776/4885KDM5B 3313/4885
US-12324452-B2 Delivery systems and methods of preparing the same MAL2, TAS2R42, TAS2R31 KDM6B 2316/4885FTO 2880/4885KDM5B 1220/4885
US-20250297398-A1 METHOD FOR DEPOSITING A ZINC-NICKEL ALLOY ON A SUBSTRATE, AN AQUEOUS ZINC-NICKEL DEPOSITION BATH, A BRIGHTENING AGENT AND USE THEREOF SLC30A7, SLC39A7, SLC30A6 KDM6B 731/4885FTO 459/4885KDM5B 656/4885
US-12419815-B2 Microcapsule compositions stabilized with viscosity control agents ACR, ALG1, MLEC KDM6B 4611/4885FTO 3822/4885KDM5B 3809/4885
US-12274771-B2 Polyurea capsule compositions PUF60, UMPS, PCBP1 KDM6B 4185/4885FTO 2589/4885KDM5B 2827/4885
US-20260041109-A1 ROBUST FLAVOR EMULSIONS ACACA, FABP4, CUTA KDM6B 4525/4885FTO 570/4885KDM5B 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.