Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315424 | 0.81 | ALDH1A3 (0.67) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL5422412 | 0.81 | ALDH1A1 (0.68) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL14542378 | 0.80 | NPC1 (0.56) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL5850854 | 0.79 | DHODH (0.57) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL1661155 | 0.73 | CASP3 (0.73) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL12422226 | 0.71 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL5738629 | 0.70 | NPC1 (0.76) | NPC1RAB9AALDH1A1KMT2APOLB | |
| Bromide SCHEMBL1983500 | 0.70 | ALDH1A1 (0.62) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL5313388 | 0.70 | NPC1 (1.00) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL31367609 | 0.70 | SSTR1 (0.50) | NPC1RAB9AALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687775-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1987-08-18 | — | — | US | disclosed |