Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869872 | 0.79 | FAAH (0.45) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10751640 | 0.79 | FAAH (0.45) | KMT2ALMNAMAPK1TP53TSHR | |
| Hydrochloric Acid SCHEMBL1315280 | 0.79 | HTR4 (0.53) | ALDH1A1KMT2AKDM4ECHRNB2CHRNB4 | |
| SCHEMBL8287645 | 0.77 | CHRM2 (0.48) | ALDH1A1MAPTKMT2AHPGDKDM4E | |
| SCHEMBL13543095 | 0.77 | CHRM1 (0.62) | ALDH1A1HTR4CNR2CHRM1CNR1 | |
| SCHEMBL11251566 | 0.76 | KMT2A (0.68) | MAPTKMT2ALMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3160698 | 0.76 | CHRM2 (0.47) | ALDH1A1MAPTKMT2AHPGDKDM4E | |
| SCHEMBL9572993 | 0.76 | SLC6A4 (0.59) | ALDH1A1MAPTKMT2ALMNAPOLB | |
| SCHEMBL10870850 | 0.75 | KDM4E (0.53) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL10751917 | 0.75 | SLC6A4 (0.53) | ALDH1A1KMT2AHPGDKDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665076-A | ANTIARRHYTHMIA AGENTS | RHONE-POULENC SANTE (FR) | 1987-05-12 | — | — | US | claimed |
| US-4665076-A | ANTIARRHYTHMIA AGENTS | RHONE-POULENC SANTE (FR) | 1987-05-12 | — | — | US | disclosed |